Bioinformatics Infrastructure Facility (BIF)

         Prof. M. Srinivasulu Reddy
         Co-Ordinator, DBT-BIF Centre
         Contact: 9866206362
         BIF: 0877 2249697   
         svucbs.btisnet@nic.in
         profmsrsvu@gmail.com

Brief summary about BIF Centre:
The Bioinformatics Infrastructure Facility (BIF) was established in the Department of Zoology, Sri Venkateswara University, Tirupati with the financial assistance from the Department of Biotechnology (DBT), New Delhi on 25th June 2010 for Bioinformatics Teaching and Research. The Centre has procured several hardwares and softwares, high speed internet and these infrastructure facilities were extended to all disciplines of Life Sciences in campus to carry out their research work and project works in the field of Bioinformatics, Biotechnology, Computational Biology, Drug Discovery, Ethanopharmacology and Human Diseases etc. The Research person working at this centre import training to the Research Scholars and PG students in Bioinformatics teaching and research activities. Further the centre has been focusing research work in Molecular Modeling, Molecular Dynamics, Drug Targeting & Drug discovery, Genomics, Proteomics, Pharmacophore, Chemoinformatics, and NGS etc., this centre has the privilege of Conducting the 26th BTIS’net Annual Co-Ordinator’s Meeting and National conferences and Bioinformatics workshops and received lot of appreciation from Researches and scientist/academicians. The Centre has received “INCENTIVE AWARD FOR PUBLICATIONS” for Two years i.e. 2014 and 2016 from DBT, New Delhi for its contributions in Biotechnology and Bioinformatics Research and Development. Data bases were developed for Cancer Genes and Markers, Alzheimer’s. New inhibitors were Identified against cancer, Human disease, Neurodegenerative disorders and Viral disease against genes/proteins. Essential gene identified as potential for drug development deposited in NCBI. One M.Phil., 19 Ph.D.’s awarded in pure Bioinformatics.

Infrastructure Facilities available and Research areas

Hardware

  • Desktop Systems  -10
  • Higher End Desktops – 06
  • Workstations – 02
  • Smart board  – 01
  • Printer – 01
  • Scanner – 01
  • Photocopier – 01
  • 5 & 5KV Power Backup
  • Along with high seep internet facility

Bioinformatics Software

  • Commercial softwares : NIL

Academic licensed :

  • Autodock,
  • PyMol,
  • HEX,
  • Z-Dock
  • Arguslab, 
  • Modeller
  • MAMD, VMD
  • ACDLabs Tools,
  • Clustal W, MEGA
  • R, NGS Analysis Tools,
  • NCBI Genome workbench
  • Ligand Scout,
  • Viewer Light etc.,

Research areas of specializations:.

  • Basic Bioinformatics research support.
  • Next Generation Sequencing Analysis by using R
  • Aquaculture and Marine-informatics
  • Neurodegenerative Disorders
  • Ethanopharmacology
  • Molecular modeling and Drug Designing
  • Molecular Dynamics and Simulation studies
  • Identification of Molecular targets and Docking studies against human Diseases.
  • Pharmacophore Analysis and QSAR studies.
  • Genomics and Evolutionary studies
  • Proteomics
  • Database development
  • Total Genome Analysis
  • DNA sequencing analysis.
  • RNA seq
  • Chip seq
  • miRNA
  • qPCR

 

R&D and Educational activities:

  • To supervise Research programmes leading to award of Ph.D. Degrees.
  • To Execute project works by M.Sc. Bioinformatics, M.Sc. Animal Biotechnology and M.Sc. Zoology students as a part of their Sc. curriculum.
  • Organization of Hands on Training Programmes for the Lectures, Ph.D., M.Phil Scholars, PG students and students of Non-Bioinformatics Programmes.
  • Insilco Molecular interactions studies on the Neurotransmitters with Seri-products.
  • Identification and molecular modeling of proteins involved in Alzheimer’s Disease and subsequent designing of novel inhibitors for these selected proteins.
  • Application of Next Generation Sequencing tool for Identification of Alzheimer’s Gene variants.
  • High throughput screening and Pharmacophore Analysis of anti- Alzheimer’s compounds.
  • Identification of New Pharmacophore compounds for Alzheimer’s Disease.
  • Genomic and Evolutionary studies on Alzheimer’s Disease causing genes.
  • Molecular dynamics and docking studies of human potassium channel.
  • Protein-Protein docking studies on AChE, Tau, B-Amyloid proteins.
  • Development of new inhibitors against breast cancer.
  • Identification and molecular modeling of proteins involved in Alzheimer’s Disease and subsequent designing of novel inhibitors for these selected proteins. 

Details about Manpower / Scientific person in the centre:

Sl. No.

Name  & Designation

Educational Qualification

Working Since

Specialization

1.

Dr. K. Peera.

Sr. Research Associate (RA) – III

(Bioinformatics Scientist)

M.Sc., Ph.D. (Bioinformatics )

01-02-2014

Molecular Biology, Drug Designing, Computational Biology, Neuroinformatics, NGS, miRNA and R programme .

Email. Drkutagollapeera2014@gmail.com.

 

Outcome from the BIF Centre

Sl. No.

Year

Total No. of Research Publication

Papers

presented

Ph.D. in bioinformatics awarded

Total PG students trained

Total Faculty

and Research Scholars trained

Patents filed/

Granted

M.Sc., Projects

Bioinformatics &

Animal Biotechnology

 Patents/ copyright filed:

 Dr. K. Peera et al.,

Ø 1st Patent Publication granted: Patent Title: *A novel medicinal …..Patent Application No.: 202141043589A. Publication Dt: 5/11/2021.

Ø 2nd Patent filling under process: Patent Title: * Formulated organic Drip Cleaner with plant growth supplements. Product name Drip Safe ™  (NPOF – ANGRU, Poshan Incubation Centre, RARS Tirupati)

 

Ø 3rd Patent filling under process: Cominational Anti-inflamatory and pain relief gel – Ayurvedic Preparation (Application submitted for YUSH apporval)

1

2015-16

33

15

3

27

12

– –

26

2

2016-17

39

35

4

73

110

– –

23

3

2017-18

23

30

2

90

83

– –

18

4

2018-19

37

32

2

95

92

– –

28

5

2019-20

35

36

2

86

30

– –

26

6

2020-21

14

6

28

0

1

0

 

Total

181

154

13

399

327

1

121

Inter-Institutional collaboration       

  • Sri Venkateswara Institute of Medical Sciences (SVIMS), Tirupati.
  • Zastra Innavoations Pvt, Banglore.
  • IGNOU, New Delhi
  • Path Gene Health Care Pvt., Ltd., Tirupati
  • Bio-Ayush Technologies Pvt., Ltd., Rangampeta, Tirupati, Andhra Pradesh
  • NBPGR, Division of Bioinformatics and Genomics, ICAR, PUSA, New Delhi.
  • SPMVV, Département of Biotechnology, Tirupati
  • Sri Sathya Sai Institute of higher learning, Bioscience, Puttaparthi.
  • ANGR Agriculture Research Station, Tirupati

Incentive Awards Received from DBT, New Delhi

Incentive Awards for Publication – 2015

Incentive Awards for Publication – 2017

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